BasicBites™ contain breakthrough technology developed at Stony Brook University

BasicBites™ contain breakthrough technology developed at Stony Brook University

From the FMS Global News Desk of Jeanne Hambleton

Released: 9-Jul-2014 9:00 AM EDT
Embargo expired: 9-Jul-2014 9:00 AM EDT
Source Newsroom:
Stony Brook University

Newswise — Stony Brook, NY, and Roslyn Heights, NY; July 9, 2014 –

A dream come “chew” for your teeth? Researchers at Stony Brook University School of Dental Medicine and Ortek Therapeutics, Inc., have developed a chocolate-flavored soft chew that is actually beneficial for your teeth.

BasicBites™ is a sugar-free chewy that helps maintain healthy teeth by supporting the normal acid-base (pH) levels that exist on tooth surfaces while coating the teeth with a mineral source.

BasicBites are designed to mimic saliva’s profound and natural benefits. It is a new oral care product that contains AlkaGen Technology™. Based on more than 40 years of research in the field of oral biology and saliva chemistry, the AlkaGen Technology was developed by Israel Kleinberg, DDS, PhD, DSc, Distinguished Professor in the Department of Oral Biology and Pathology, and Director of the Division of Translational Oral Biology at Stony Brook.

Internationally recognized in the field of salivary and microbial research, Dr. Kleinberg has spent decades investigating the biochemistry and physiology of human mixed bacterial communities, especially those in the mouth that interact with saliva in supporting oral health. His findings and subsequent research led to the development of AlkaGen Technology.

The saliva-mimicking technology in BasicBites consists of two main ingredients – arginine bicarbonate and calcium carbonate. Arginine is a common amino acid found in saliva and is naturally present in many foods. Arginine supports the sustained base or alkali production on the surfaces of the teeth. This helps keep tooth surfaces in the existing normal pH range, allowing the calcium to coat and support healthy tooth structure.

“The ingredients in BasicBites mirror the vital nutrients  found in healthy saliva, ” says Dr. Kleinberg.

“We spent decades analyzing and literally taking apart saliva, and we eventually solved the puzzle of the protective and natural benefits of saliva. This has led to a new paradigm in the science of oral care. Keeping the pH of teeth in balance is extremely important. This is especially critical for individuals with dry mouth and those who consume excessive acid rich foods and beverages.”

“The technology in BasicBites is recognized as a major breakthrough in oral care,” said Mitchell Goldberg, President of Ortek.

“We all want to support the health of our teeth, and BasicBites are a delicious and portable oral care product based on incredible research and scientific results.”

According to Peter Donnelly, Director of Stony Brook’s Office of Technology Licensing and Industry Relations, the introduction of BasicBites is another example of the long-standing and commercially successful research and licensing collaboration between Stony Brook and Ortek.

This technology breakthrough was a team effort that included support from Stony Brook University’s Center for Biotechnology, and the collaborative work of the Office of Technology Licensing and Industry Relations with the School of Dental Medicine at Stony Brook University.

BasicBites, 20 calories per piece, is available exclusively from Ortek via its website, Two bites a day will do the trick.. but sold in the USA……..




Source Newsroom: University of Adelaide

Citations The Journal of Neuroscience   

Newswise — University of Adelaide researchers have discovered the first evidence that the nerves in the stomach act as a circadian clock, limiting food intake to specific times of the day.

The discovery, published in The Journal of Neuroscience, could lead to new information about how the gut signals to our brains about when we are full, and when to keep eating.

In the University’s Nerve-Gut Research Laboratory, Dr Stephen Kentish investigated how the nerves in the stomach respond to stretch, which occurs as a consequence of food intake, at three-hourly intervals across one day.

“These nerves are responsible for letting the brain know how much food we have eaten and when to stop eating,” says Dr Kentish, who is the lead author of the paper.

“What we have found is that the nerves in the gut are at their least sensitive at time periods associated with being awake. This means more food can be consumed before we feel full at times of high activity, when more energy is required.

“However, with a change in the day-night cycle to a period associated with sleeping, the nerves in the stomach become more sensitive to stretch, signaling fullness to the brain quicker and thus limiting food intake. This variation repeats every 24 hours in a circadian manner, with the nerves acting as a clock to coordinate food intake with energy requirements,” he says.

So far this discovery has been made in laboratory studies, not in humans.

“Our theory is that the same variations in nerve responses exist in human stomachs, with the gut nerves being less sensitive to fullness during the day and more sensitive at night,” Dr Kentish says.

Study leader Associate Professor Amanda Page says this research could lead to further discoveries about how changes in people’s circadian clocks affect their eating habits.

“We know that shift workers, for example, are more prone to disruptions in sleep and eating behavior, leading to obesity and other health problems. We are now conducting further research to see what kind of impact such changes to the circadian rhythm will have on eating behavior, and how the nerves in the stomach react to those changes,” Associate Professor Page says.

This study has been funded by the National Health and Medical Research Council (NHMRC).

My comments

What a pity our stomach  or even our head  does not tell us if we eat five more mouthfuls  we will add five pounds to our weight. Even if it said your little black dress will not fit you if you eat that chocolate, it would help.  I just get carried way  when eating a cream doughnut or some nice chocolates.  I imagine it would help a lot of us if we had that built warning. 

YesI I  heard  what you said!  “What happened to will power? ” But I lose  my will power when cream cakes and strawberries and cream are on offer . Back tomorrow and by then thinking thin. Jeanne 


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